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References

    1. Ohsawa I, Ishikawa M, Takahashi M, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nature Medicine. 2007;13(6):688-694. https://doi.org/10.1038/nm1577
    2. Molecular Hydrogen Institute. Human Studies Research Bibliography. 2024. https://molecularhydrogeninstitute.org/human-studies/
    3. Ostojic SM, et al. Molecular and cellular mechanisms associated with effects of molecular hydrogen in cardiovascular and central nervous systems. Frontiers in Physiology. 2020. https://pmc.ncbi.nlm.nih.gov/articles/PMC7765453/
    4. Ohta S. Molecular hydrogen may activate the transcription factor Nrf2 to alleviate oxidative stress through the hydrogen-targeted porphyrin. Aging Pathobiology and Therapeutics. 2023;5(1):25-32. http://www.antpublisher.com/index.php/APT/article/download/566/692 Zhai X, et al. Molecular hydrogen protects against oxidative stress-induced RAW 264.7 macrophage cells through the activation of Nrf2 and inhibition of MAPK signaling pathway. Molecular & Cellular Toxicology. 2020. https://link.springer.com/article/10.1007/s13273-020-00074-w
    5. Mikami T, et al. Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study. Canadian Journal of Physiology and Pharmacology. 2019;97(9):857-862. https://doi.org/10.1139/cjpp-2019-0059
    6. Nishimaki K, et al. Effects of molecular hydrogen assessed by an animal model and a randomized clinical study on mild cognitive impairment. Current Alzheimer Research. 2018;15(1):1-9. https://pubmed.ncbi.nlm.nih.gov/29110615/
    1. Mizuno K, et al. Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life. Medical Gas Research. 2017;7(4):247-255. https://pmc.ncbi.nlm.nih.gov/articles/PMC5806445/
    2. Aoki K, et al. Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research. 2012;2(1):12. https://pmc.ncbi.nlm.nih.gov/articles/PMC3395574/
    3. Sladečková B, et al. Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial. Frontiers in Physiology. 2024;15:1321160. https://pmc.ncbi.nlm.nih.gov/articles/PMC11046232/
    4. Sim M, et al. Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial. Scientific Reports. 2020;10:12130. https://www.nature.com/articles/s41598-020-68930-2
    5. Zanini D, et al. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Experimental Gerontology. 2021;155:111574. https://www.sciencedirect.com/science/article/abs/pii/S0531556521003569

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